Adult neuropsychiatry is now a well-established field with numerous reputable references. Practitioners who work with children routinely note how references and practitioners knowledgeable in the equivalent work in the pediatric world are rare. Child psychiatrists and neurologists frequently work with individuals struggling with these conditions and would strongly benefit from such a reference that incorporates medical work-up, psychopharmacological recommendations, family/support recommendations and theoretical pathophysiology. Pediatricians and developmental pediatricians often treat children with behavioral and neuropsychiatric sequelae, but are not well-trained in the neuropsychiatric management of these cases. Neuropsychologists and educational psychologists working with children and adults with pediatric-onset conditions will also find the text helpful to contextualize their cases, better-understand the medical evaluation and management and perhaps adjust recommendations that would supplement their own testing methods. Finally, sub-specialists in adult neurology, psychiatry and neuropsychiatry often find themselves working with these children by default as there are few pediatric subspecialists who are available to accept them into practice. When facing complex neuropsychiatric illness in children, many clinicians are stymied because they may have “never seen a case like that”.